1-Methyl-1H-pyrazole-3,5-dicarboxylic acid
1-Methyl-1H-pyrazole-3,5-dicarboxylic acid
CAS:
Molecular Formula: C6H6N2O4
1-Methyl-1H-pyrazole-3,5-dicarboxylic acid - Names and Identifiers
1-Methyl-1H-pyrazole-3,5-dicarboxylic acid - Physico-chemical Properties
| Molecular Formula | C6H6N2O4 |
| Molar Mass | 170.12 |
| Storage Condition | 2-8℃ |
1-Methyl-1H-pyrazole-3,5-dicarboxylic acid - Introduction
1-Methyl-1H-pyrazole-3,5-dicarboxylic acid is an organic compound with the chemical formula C7H6N2O4.
Nature:
-Appearance: White or off-white crystalline powder
-Solubility: Soluble in water and commonly used organic solvents, such as alcohols and ketones
-Melting point: About 215-225 degrees Celsius
Use:
1-methyll-1h-pyrazole-3, 5-dicarboxylic acid is mainly used as an intermediate in organic synthesis and is widely used in the fields of medicine, dyes and pesticides. It can be used as a raw material for the preparation of a variety of organic compounds, such as drugs, pigments and functional materials.
Method:
The preparation of 1-methyll-1h-pyrazole-3, 5-dicarboxylic acid can be carried out by the following steps:
1. The first pyrazole and sodium hydroxide in alcohol solvent reaction, generate sodium pyrazole salt.
2. Formaldehyde and dichloromethane were added to the reaction system and heated to reflux to obtain 2,5-bis (formyl) pyrazole compound.
3. Finally, the diethyl dicarboxylate is deesterized and reacted with the compound obtained in the previous step to obtain 1-Methyl-1H-pyrazole-3,5-dicarboxylic acid.
Safety Information:
1-methyll-1h-pyrazole-3, 5-dicarboxylic acid is relatively safe for use under regular laboratory conditions. However, as a chemical, it is still subject to regular safe practices. For any chemical, including this compound, it is necessary to wear gloves and laboratory protective glasses during handling to avoid contact with skin and inhalation of dust. Keep away from ignition and flammable substances when stored and handled.
Nature:
-Appearance: White or off-white crystalline powder
-Solubility: Soluble in water and commonly used organic solvents, such as alcohols and ketones
-Melting point: About 215-225 degrees Celsius
Use:
1-methyll-1h-pyrazole-3, 5-dicarboxylic acid is mainly used as an intermediate in organic synthesis and is widely used in the fields of medicine, dyes and pesticides. It can be used as a raw material for the preparation of a variety of organic compounds, such as drugs, pigments and functional materials.
Method:
The preparation of 1-methyll-1h-pyrazole-3, 5-dicarboxylic acid can be carried out by the following steps:
1. The first pyrazole and sodium hydroxide in alcohol solvent reaction, generate sodium pyrazole salt.
2. Formaldehyde and dichloromethane were added to the reaction system and heated to reflux to obtain 2,5-bis (formyl) pyrazole compound.
3. Finally, the diethyl dicarboxylate is deesterized and reacted with the compound obtained in the previous step to obtain 1-Methyl-1H-pyrazole-3,5-dicarboxylic acid.
Safety Information:
1-methyll-1h-pyrazole-3, 5-dicarboxylic acid is relatively safe for use under regular laboratory conditions. However, as a chemical, it is still subject to regular safe practices. For any chemical, including this compound, it is necessary to wear gloves and laboratory protective glasses during handling to avoid contact with skin and inhalation of dust. Keep away from ignition and flammable substances when stored and handled.
Last Update：2024-04-09 21:00:56
